Ekman-Larsson was selected sixth overall by Phoenix in the 2009 NHL Entry Draft. On May 24th 2010. During his time with the Coyotes wore number 23. On July 23rd 2021, Ekman-Larsson waived his no-movement clause and was traded, along with
Conor Garland, to the Vancouver Canucks in exchange for Jay Beagle, Loui Eriksson, Antoine Roussel, a 2021 first-round pick (
Dylan Guenther), a 2022 second-round pick and a 2023 seventh-round pick. While a member of the Canucks wore number 23.